Cell walls for medical coating

The objective of the project is to address problems pertaining to the integration of bone contacting devices, in particular with regard to integration in poor quality bone.  

Bone contacting implants are widely used for e.g orthopedic, maxillofacial and dental applications.

 

New developments in surface topographies of titanium surfaces have resulted in increased success rates. However, in situations with compromised bone quality e.g. osteoporotic bone and in bone transplants, improvement is very much needed.

 

Our research project is focused on addressing these issues by increasing the biocompatibility of the titanium implant by a coating material. We will design, synthesize and use novel pectic polysaccharides for coating of implants and employ state of the art nanotechology methods for surface derivatisation and characterization, and use both in vitro and in vivo methods for gauging mammalian cell and tissue responses to the grafted surfaces.