Redox regulation

Important structural and catalytic functions of many enzymes are dependent on regulation determined by the redox state of the cell. In the chloroplast, reducing equivalents produced during the day by photosynthesis are transported from photosystem I via the ferredoxin-thioredoxin system to the target proteins. Hence, this system links enzyme activity to light, ensuring coordination between photosynthesis and metabolism by reductive activation of enzymes during the day.  

 

Using an activity screen we have identified a number of redox regulated degradative and biosynthetic enzymes involved in starch metabolism. Our data provides evidence for the presence of a coordinated regulative mechanism of starch biosynthesis and degradation.

 

Selected publications
Blennow, A. and Svensson,. B. (2010) Dynamics of starch granule biogenesis – the role of redox regulated enzymes and low affinity CBMs, Biocatalysis and Biotransformation, 28 (1) 3-9.